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The role of Xist‐mediated Polycomb recruitment in the initiation of X‐chromosome inactivation
Xist RNA has been established as the master regulator of X‐chromosome inactivation (XCI) in female eutherian mammals, but its mechanism of action remains unclear. By creating novel Xist‐inducible mutants at the endogenous locus in male mouse embryonic stem (ES) cells, we dissect the role of the cons...
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| Udgivet i: | EMBO Rep |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6776897/ https://ncbi.nlm.nih.gov/pubmed/31456285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201948019 |
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