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The role of Xist‐mediated Polycomb recruitment in the initiation of X‐chromosome inactivation

Xist RNA has been established as the master regulator of X‐chromosome inactivation (XCI) in female eutherian mammals, but its mechanism of action remains unclear. By creating novel Xist‐inducible mutants at the endogenous locus in male mouse embryonic stem (ES) cells, we dissect the role of the cons...

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Dades bibliogràfiques
Publicat a:EMBO Rep
Autors principals: Bousard, Aurélie, Raposo, Ana Cláudia, Żylicz, Jan Jakub, Picard, Christel, Pires, Vanessa Borges, Qi, Yanyan, Gil, Cláudia, Syx, Laurène, Chang, Howard Y, Heard, Edith, da Rocha, Simão Teixeira
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776897/
https://ncbi.nlm.nih.gov/pubmed/31456285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201948019
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