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Xist Yeast Artificial Chromosome Transgenes Function as X-Inactivation Centers Only in Multicopy Arrays and Not as Single Copies

X-chromosome inactivation in female mammals is controlled by the X-inactivation center (Xic). This locus is required for inactivation in cis and is thought to be involved in the counting process which ensures that only a single X chromosome remains active per diploid cell. The Xist gene maps to the...

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Détails bibliographiques
Auteurs principaux: Heard, Edith, Mongelard, Fabien, Arnaud, Danielle, Avner, Philip
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC84109/
https://ncbi.nlm.nih.gov/pubmed/10082582
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