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Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass
X-chromosome inactivation is established during early development. In mice, transcriptional repression of the paternal X-chromosome (Xp) and enrichment in epigenetic marks such as H3K27me3 is achieved by the early blastocyst stage. X-chromosome inactivation is then reversed in the inner cell mass. T...
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Publicado no: | Nat Commun |
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Main Authors: | , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group UK
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5670228/ https://ncbi.nlm.nih.gov/pubmed/29101321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01415-5 |
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