Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass

X-chromosome inactivation is established during early development. In mice, transcriptional repression of the paternal X-chromosome (Xp) and enrichment in epigenetic marks such as H3K27me3 is achieved by the early blastocyst stage. X-chromosome inactivation is then reversed in the inner cell mass. T...

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Published in:Nat Commun
Main Authors: Borensztein, Maud, Okamoto, Ikuhiro, Syx, Laurène, Guilbaud, Guillaume, Picard, Christel, Ancelin, Katia, Galupa, Rafael, Diabangouaya, Patricia, Servant, Nicolas, Barillot, Emmanuel, Surani, Azim, Saitou, Mitinori, Chen, Chong-Jian, Anastassiadis, Konstantinos, Heard, Edith
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5670228/
https://ncbi.nlm.nih.gov/pubmed/29101321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01415-5
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