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Initiation of epigenetic reprogramming of the X chromosome in somatic nuclei transplanted to a mouse oocyte

The active and inactive X chromosomes have distinct epigenetic marks in somatic nuclei, which undergo reprogramming after transplantation into oocytes. We show that, despite the disappearance of Xist RNA coating in 30 min, the epigenetic memory of the inactive X persists with the precocious appearan...

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Detalhes bibliográficos
Main Authors: Bao, Siqin, Miyoshi, Naoki, Okamoto, Ikuhiro, Jenuwein, Thomas, Heard, Edith, Azim Surani, M
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369137/
https://ncbi.nlm.nih.gov/pubmed/16007070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400461
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