Initiation of epigenetic reprogramming of the X chromosome in somatic nuclei transplanted to a mouse oocyte

The active and inactive X chromosomes have distinct epigenetic marks in somatic nuclei, which undergo reprogramming after transplantation into oocytes. We show that, despite the disappearance of Xist RNA coating in 30 min, the epigenetic memory of the inactive X persists with the precocious appearan...

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Bibliografiske detaljer
Main Authors: Bao, Siqin, Miyoshi, Naoki, Okamoto, Ikuhiro, Jenuwein, Thomas, Heard, Edith, Azim Surani, M
Format: Artigo
Sprog:Inglês
Udgivet: 2005
Fag:
Scientific Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369137/
https://ncbi.nlm.nih.gov/pubmed/16007070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400461
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