Histone H3 lysine 4 methylation is associated with the transcriptional reprogramming efficiency of somatic nuclei by oocytes

BACKGROUND: When the nuclei of mammalian somatic cells are transplanted to amphibian oocytes in the first meiotic prophase, they are rapidly induced to begin transcribing several pluripotency genes, including Sox2 and Oct4. The more differentiated the donor cells of the nuclei, the longer it takes f...

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Bibliographic Details
Main Authors: Murata, Kazutaka, Kouzarides, Tony, Bannister, Andrew J, Gurdon, John B
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829560/
https://ncbi.nlm.nih.gov/pubmed/20181087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-3-4
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