Xist-dependent imprinted X inactivation and the early developmental consequences of its failure

The long non-coding RNA Xist is only expressed from the paternal X chromosome in mouse pre-implantation female embryos and leads to its transcriptional silencing. In females, absence of Xist leads to post-implantation lethality. Here we report that the initiation of imprinted XCI absolutely requires...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Struct Mol Biol
Egile Nagusiak: Borensztein, Maud, Syx, Laurène, Ancelin, Katia, Diabangouaya, Patricia, Picard, Christel, Liu, Tao, Liang, Jun-Bin, Vassilev, Ivaylo, Galupa, Rafael, Servant, Nicolas, Barillot, Emmanuel, Surani, Azim, Chen, Chong-Jian, Heard, Edith
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5337400/
https://ncbi.nlm.nih.gov/pubmed/28134930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3365
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak