Inhibition of Hepatitis C Virus Replication by GS-6620, a Potent C-Nucleoside Monophosphate Prodrug

As a class, nucleotide inhibitors (NIs) of the hepatitis C virus (HCV) nonstructural protein 5B (NS5B) RNA-dependent RNA polymerase offer advantages over other direct-acting antivirals, including properties, such as pangenotype activity, a high barrier to resistance, and reduced potential for drug-d...

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Bibliografiset tiedot
Päätekijät: Feng, Joy Y., Cheng, Guofeng, Perry, Jason, Barauskas, Ona, Xu, Yili, Fenaux, Martijn, Eng, Stacey, Tirunagari, Neeraj, Peng, Betty, Yu, Mei, Tian, Yang, Lee, Yu-Jen, Stepan, George, Lagpacan, Leanna L., Jin, Debi, Hung, Magdeleine, Ku, Karin S., Han, Bin, Kitrinos, Kathryn, Perron, Michel, Birkus, Gabriel, Wong, Kelly A., Zhong, Weidong, Kim, Choung U., Carey, Anne, Cho, Aesop, Ray, Adrian S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2014
Aiheet:
Antiviral Agents
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023746/
https://ncbi.nlm.nih.gov/pubmed/24419349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02351-13
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