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Cardiac Myocyte Z-line Calmodulin is Mainly RyR2-Bound and Reduction is Arrhythmogenic and Occurs in Heart Failure
RATIONALE: Calmodulin (CaM) associates with cardiac ryanodine receptors (RyR2) as an important regulator. Defective CaM-RyR2 interaction may occur in heart failure (HF), cardiac hypertrophy, and catecholaminergic polymorphic ventricular tachycardia (CPVT). However, the in situ binding properties for...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4004530/ https://ncbi.nlm.nih.gov/pubmed/24186966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.114.302857 |
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