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FRET Detection of Calmodulin Binding to the Cardiac RyR2 Calcium Release Channel
Calmodulin (CaM) binding to the type 2 ryanodine receptor (RyR2) regulates Ca release from the cardiac sarcoplasmic reticulum (SR). However, the structural basis of CaM regulation of the RyR2 is poorly defined, and the presence of other potential CaM binding partners in cardiac myocytes complicates...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Biophysical Society
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3207159/ https://ncbi.nlm.nih.gov/pubmed/22067155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.09.030 |
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