FRET Detection of Calmodulin Binding to the Cardiac RyR2 Calcium Release Channel

Calmodulin (CaM) binding to the type 2 ryanodine receptor (RyR2) regulates Ca release from the cardiac sarcoplasmic reticulum (SR). However, the structural basis of CaM regulation of the RyR2 is poorly defined, and the presence of other potential CaM binding partners in cardiac myocytes complicates...

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Main Authors: Guo, Tao, Fruen, Bradley R., Nitu, Florentin R., Nguyen, Trinh D., Yang, Yi, Cornea, Razvan L., Bers, Donald M.
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2011
Assuntos:
Channels and Transporters
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207159/
https://ncbi.nlm.nih.gov/pubmed/22067155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.09.030
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