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FRET-based mapping of calmodulin bound to the RyR1 Ca(2+) release channel
Calmodulin (CaM) functions as a regulatory subunit of ryanodine receptor (RyR) channels, modulating channel activity in response to changing [Ca(2+)](i). To investigate the structural basis of CaM regulation of the RyR1 isoform, we used site-directed labeling of channel regulatory subunits and fluor...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2662960/ https://ncbi.nlm.nih.gov/pubmed/19332786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813010106 |
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