Impaired Learning and Motor Behavior in Heterozygous Pafah1b1 (Lis1) Mutant Mice

Heterozygous mutation or deletion of Pafah1b1 (LIS1) in humans is associated with syndromes with type 1 lissencephaly, a severe brain developmental disorder resulting from abnormal neuronal migration. We have created Lis1 heterozygous mutant mice by gene targeting. Heterozygous mutant mice are viabl...

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Detalhes bibliográficos
Publicado no:Learn Mem
Main Authors: Paylor, Richard, Hirotsune, Shinji, Gambello, Michael J., Yuva-Paylor, Lisa, Crawley, Jacqueline N., Wynshaw-Boris, Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1999
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC311310/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10541472/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/lm.6.5.521
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