Impaired Learning and Motor Behavior in Heterozygous Pafah1b1 (Lis1) Mutant Mice
Heterozygous mutation or deletion of Pafah1b1 (LIS1) in humans is associated with syndromes with type 1 lissencephaly, a severe brain developmental disorder resulting from abnormal neuronal migration. We have created Lis1 heterozygous mutant mice by gene targeting. Heterozygous mutant mice are viabl...
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| Опубликовано в:: | Learn Mem |
|---|---|
| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
1999
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC311310/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10541472/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/lm.6.5.521 |
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