ロード中...

A Low-Molecular-Weight Antagonist for the Human Thyrotropin Receptor with Therapeutic Potential for Hyperthyroidism

Low-molecular-weight (LMW) antagonists for TSH receptor (TSHR) may have therapeutic potential as orally active drugs to block stimulating antibodies (TsAbs) in Graves’ hyperthyroidism. We describe an approach to identify LMW ligands for TSHR based on Org41841, a LMW partial agonist for the LH/chorio...

詳細記述

保存先:
書誌詳細
主要な著者: Neumann, Susanne, Kleinau, Gunnar, Costanzi, Stefano, Moore, Susanna, Jiang, Jian-kang, Raaka, Bruce M., Thomas, Craig J., Krause, Gerd, Gershengorn, Marvin C.
フォーマット: Artigo
言語:Inglês
出版事項: The Endocrine Society 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613050/
https://ncbi.nlm.nih.gov/pubmed/18669595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-0836
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!