A Low-Molecular-Weight Antagonist for the Human Thyrotropin Receptor with Therapeutic Potential for Hyperthyroidism

Low-molecular-weight (LMW) antagonists for TSH receptor (TSHR) may have therapeutic potential as orally active drugs to block stimulating antibodies (TsAbs) in Graves’ hyperthyroidism. We describe an approach to identify LMW ligands for TSHR based on Org41841, a LMW partial agonist for the LH/chorio...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Main Authors: Neumann, Susanne, Kleinau, Gunnar, Costanzi, Stefano, Moore, Susanna, Jiang, Jian-kang, Raaka, Bruce M., Thomas, Craig J., Krause, Gerd, Gershengorn, Marvin C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Endocrine Society 2008
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613050/
https://ncbi.nlm.nih.gov/pubmed/18669595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-0836
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla