A Low-Molecular-Weight Antagonist for the Human Thyrotropin Receptor with Therapeutic Potential for Hyperthyroidism

Low-molecular-weight (LMW) antagonists for TSH receptor (TSHR) may have therapeutic potential as orally active drugs to block stimulating antibodies (TsAbs) in Graves’ hyperthyroidism. We describe an approach to identify LMW ligands for TSHR based on Org41841, a LMW partial agonist for the LH/chorio...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Neumann, Susanne, Kleinau, Gunnar, Costanzi, Stefano, Moore, Susanna, Jiang, Jian-kang, Raaka, Bruce M., Thomas, Craig J., Krause, Gerd, Gershengorn, Marvin C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2008
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613050/
https://ncbi.nlm.nih.gov/pubmed/18669595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-0836
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados