Specific isoforms of Drosophila Shroom define spatial requirements for the induction of apical constriction

Por Bolinger, Cory, Zasadil, Lauren, Rizaldy, Ryan, Hildebrand, Jeffrey D.
Publicado em 2010

Living in CIN: mitotic infidelity and its consequences for tumor promotion and suppression

Por Funk, Laura C., Zasadil, Lauren M., Weaver, Beth A.
Publicado no Dev Cell (2016)

2n or not 2n: Aneuploidy, polyploidy and chromosomal instability in primary and tumor cells

Por Zasadil, Lauren M., Britigan, Eric M.C., Weaver, Beth A.
Publicado em 2013

The ARF tumor suppressor prevents chromosomal instability and ensures mitotic checkpoint fidelity through regulation of Aurora B

Por Britigan, Eric M.C., Wan, Jun, Zasadil, Lauren M., Ryan, Sean D., Weaver, Beth A.
Publicado em 2014

The role of microtubules in neutrophil polarity and migration in live zebrafish

Por Yoo, Sa Kan, Lam, Pui-ying, Eichelberg, Mark R., Zasadil, Lauren, Bement, William M., Huttenlocher, Anna
Publicado em 2012

Centrosome amplification induces high grade features and is prognostic of worse outcomes in breast cancer

Por Denu, Ryan A., Zasadil, Lauren M., Kanugh, Craig, Laffin, Jennifer, Weaver, Beth A., Burkard, Mark E.
Publicado no BMC Cancer (2016)

Chromosome missegregation rate predicts whether aneuploidy will promote or suppress tumors

Por Silk, Alain D., Zasadil, Lauren M., Holland, Andrew J., Vitre, Benjamin, Cleveland, Don W., Weaver, Beth A.
Publicado em 2013

Up-regulation of the mitotic checkpoint component Mad1 causes chromosomal instability and resistance to microtubule poisons

Por Ryan, Sean D., Britigan, Eric M. C., Zasadil, Lauren M., Witte, Kristen, Audhya, Anjon, Roopra, Avtar, Weaver, Beth A.
Publicado em 2012

A Golgi localized pool of the mitotic checkpoint component Mad1 controls integrin secretion and cell migration

Por Wan, Jun, Zhu, Fen, Zasadil, Lauren M., Yu, Jiaquan, Wang, Lei, Johnson, Adam, Berthier, Erwin, Beebe, David J., Audhya, Anjon, Weaver, Beth A.
Publicado no Curr Biol (2014)

High rates of chromosome missegregation suppress tumor progression but do not inhibit tumor initiation

Por Zasadil, Lauren M., Britigan, Eric M. C., Ryan, Sean D., Kaur, Charanjeet, Guckenberger, David J., Beebe, David J., Moser, Amy R., Weaver, Beth A.
Publicado no Mol Biol Cell (2016)

Chromosome mis-segregation generates cell cycle-arrested cells with complex karyotypes that are eliminated by the immune system

Por Santaguida, Stefano, Richardson, Amelia, Iyer, Divya Ramalingam, M’Saad, Ons, Zasadil, Lauren, Knouse, Kristin A., Wong, Yao Liang, Rhind, Nicholas, Desai, Arshad, Amon, Angelika
Publicado no Dev Cell (2017)

Cytotoxicity of paclitaxel in breast cancer is due to chromosome missegregation on multipolar spindles

Por Zasadil, Lauren M., Andersen, Kristen A., Yeum, Dabin, Rocque, Gabrielle B., Wilke, Lee G., Tevaarwerk, Amye J., Raines, Ronald T., Burkard, Mark E., Weaver, Beth A.
Publicado em 2014

Identification of selective lead compounds for treatment of high-ploidy breast cancer

Por Choudhary, Alka, Zachek, Brittany, Lera, Robert F., Zasadil, Lauren M., Lasek, Amber, Denu, Ryan A., Kim, Hyunjung, Kanugh, Craig, Laffin, Jennifer J., Harter, Josephine M., Wisinski, Kari B., Saha, Sandeep, Weaver, Beth A., Burkard, Mark E.
Publicado no Mol Cancer Ther (2015)