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Living in CIN: mitotic infidelity and its consequences for tumor promotion and suppression
Errors in chromosome segregation during mitosis have been recognized as a hallmark of tumor cells since the late 1800s, resulting in the long-standing hypothesis that mitotic abnormalities drive tumorigenesis. Recent work has shown that mitotic defects can promote tumors, suppress them, or do neithe...
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| Publicado no: | Dev Cell |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5204306/ https://ncbi.nlm.nih.gov/pubmed/27997823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2016.10.023 |
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