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Chromosome missegregation rate predicts whether aneuploidy will promote or suppress tumors

Aneuploidy, a chromosome content other than a multiple of the haploid number, is a common feature of cancer cells. Whole chromosomal aneuploidy accompanying ongoing chromosomal instability in mice resulting from reduced levels of the centromere-linked motor protein CENP-E has been reported to increa...

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Bibliografiske detaljer
Main Authors: Silk, Alain D., Zasadil, Lauren M., Holland, Andrew J., Vitre, Benjamin, Cleveland, Don W., Weaver, Beth A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816416/
https://ncbi.nlm.nih.gov/pubmed/24133140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1317042110
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