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High rates of chromosome missegregation suppress tumor progression but do not inhibit tumor initiation
Aneuploidy, an abnormal chromosome number that deviates from a multiple of the haploid, has been recognized as a common feature of cancers for >100 yr. Previously, we showed that the rate of chromosome missegregation/chromosomal instability (CIN) determines the effect of aneuploidy on tumors; whe...
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| Published in: | Mol Biol Cell |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
The American Society for Cell Biology
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4927272/ https://ncbi.nlm.nih.gov/pubmed/27146113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-10-0747 |
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