High rates of chromosome missegregation suppress tumor progression but do not inhibit tumor initiation

Aneuploidy, an abnormal chromosome number that deviates from a multiple of the haploid, has been recognized as a common feature of cancers for >100 yr. Previously, we showed that the rate of chromosome missegregation/chromosomal instability (CIN) determines the effect of aneuploidy on tumors; whe...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Mol Biol Cell
Huvudupphovsmän: Zasadil, Lauren M., Britigan, Eric M. C., Ryan, Sean D., Kaur, Charanjeet, Guckenberger, David J., Beebe, David J., Moser, Amy R., Weaver, Beth A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Cell Biology 2016
Ämnen:
Brief Reports
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4927272/
https://ncbi.nlm.nih.gov/pubmed/27146113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-10-0747
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk