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A Golgi localized pool of the mitotic checkpoint component Mad1 controls integrin secretion and cell migration

Mitotic arrest deficient 1 (Mad1) plays a well-characterized role in the major cell cycle checkpoint that regulates chromosome segregation during mitosis, the mitotic checkpoint (also known as the spindle assembly checkpoint). During mitosis, Mad1 recruits Mad2 to unattached kinetochores [1, 2], whe...

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Vydáno v:Curr Biol
Hlavní autoři: Wan, Jun, Zhu, Fen, Zasadil, Lauren M., Yu, Jiaquan, Wang, Lei, Johnson, Adam, Berthier, Erwin, Beebe, David J., Audhya, Anjon, Weaver, Beth A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254593/
https://ncbi.nlm.nih.gov/pubmed/25447996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2014.09.052
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