A carregar...

Up-regulation of the mitotic checkpoint component Mad1 causes chromosomal instability and resistance to microtubule poisons

The mitotic checkpoint is the major cell cycle checkpoint acting during mitosis to prevent aneuploidy and chromosomal instability, which are hallmarks of tumor cells. Reduced expression of the mitotic checkpoint component Mad1 causes aneuploidy and promotes tumors in mice [Iwanaga Y, et al. (2007) C...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ryan, Sean D., Britigan, Eric M. C., Zasadil, Lauren M., Witte, Kristen, Audhya, Anjon, Roopra, Avtar, Weaver, Beth A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421180/
https://ncbi.nlm.nih.gov/pubmed/22778409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201911109
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!