Up-regulation of the mitotic checkpoint component Mad1 causes chromosomal instability and resistance to microtubule poisons

Eitemau Tebyg

• The ARF tumor suppressor prevents chromosomal instability and ensures mitotic checkpoint fidelity through regulation of Aurora B
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  Cyhoeddwyd: (2014)
• A Golgi localized pool of the mitotic checkpoint component Mad1 controls integrin secretion and cell migration
  gan: Wan, Jun, et al.
  Cyhoeddwyd: (2014)
• 2n or not 2n: Aneuploidy, polyploidy and chromosomal instability in primary and tumor cells
  gan: Zasadil, Lauren M., et al.
  Cyhoeddwyd: (2013)
• Tpr directly binds to Mad1 and Mad2 and is important for the Mad1–Mad2-mediated mitotic spindle checkpoint
  gan: Lee, Sang Hyun, et al.
  Cyhoeddwyd: (2008)
• HAT cofactor Trrap regulates the mitotic checkpoint by modulation of Mad1 and Mad2 expression
  gan: Li, Hai, et al.
  Cyhoeddwyd: (2004)