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Centrosome amplification induces high grade features and is prognostic of worse outcomes in breast cancer

BACKGROUND: Centrosome amplification (CA) has been reported in nearly all types of human cancer and is associated with deleterious clinical factors such as higher grade and stage. However, previous reports have not shown how CA affects cellular differentiation and clinical outcomes in breast cancer....

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Denu, Ryan A., Zasadil, Lauren M., Kanugh, Craig, Laffin, Jennifer, Weaver, Beth A., Burkard, Mark E.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734858/
https://ncbi.nlm.nih.gov/pubmed/26832928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2083-x
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