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Centrosome amplification induces high grade features and is prognostic of worse outcomes in breast cancer

BACKGROUND: Centrosome amplification (CA) has been reported in nearly all types of human cancer and is associated with deleterious clinical factors such as higher grade and stage. However, previous reports have not shown how CA affects cellular differentiation and clinical outcomes in breast cancer....

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Podrobná bibliografie
Vydáno v:BMC Cancer
Hlavní autoři: Denu, Ryan A., Zasadil, Lauren M., Kanugh, Craig, Laffin, Jennifer, Weaver, Beth A., Burkard, Mark E.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734858/
https://ncbi.nlm.nih.gov/pubmed/26832928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2083-x
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