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Centriole Overduplication is the Predominant Mechanism Leading to Centrosome Amplification in Melanoma

Centrosome amplification (CA) is common in cancer and can arise by centriole overduplication or by cell doubling events, including the failure of cell division and cell-cell fusion. To assess the relative contributions of these two mechanisms, the number of centrosomes with mature/mother centrioles...

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Bibliographic Details
Published in:Mol Cancer Res
Main Authors: Denu, Ryan A., Shabbir, Maria, Nihal, Minakshi, Singh, Chandra K., Longley, B. Jack, Burkard, Mark E., Ahmad, Nihal
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835182/
https://ncbi.nlm.nih.gov/pubmed/29330283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0197
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