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Centriole Overduplication is the Predominant Mechanism Leading to Centrosome Amplification in Melanoma

Centrosome amplification (CA) is common in cancer and can arise by centriole overduplication or by cell doubling events, including the failure of cell division and cell-cell fusion. To assess the relative contributions of these two mechanisms, the number of centrosomes with mature/mother centrioles...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Denu, Ryan A., Shabbir, Maria, Nihal, Minakshi, Singh, Chandra K., Longley, B. Jack, Burkard, Mark E., Ahmad, Nihal
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835182/
https://ncbi.nlm.nih.gov/pubmed/29330283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0197
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