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Dynamics of centriole amplification in centrosome-depleted brain multiciliated progenitors

Reproductive and respiratory organs, along with brain ventricles, are lined by multiciliated epithelial cells (MCC) that generate cilia-powered fluid flows. MCC hijack the centrosome duplication pathway to form hundreds of centrioles and nucleate motile cilia. In these cells, the large majority of p...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Mercey, Olivier, Al Jord, Adel, Rostaing, Philippe, Mahuzier, Alexia, Fortoul, Aurélien, Boudjema, Amélie-Rose, Faucourt, Marion, Spassky, Nathalie, Meunier, Alice
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736942/
https://ncbi.nlm.nih.gov/pubmed/31506528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49416-2
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