Retinoblastoma protein induction by HIV viremia or CCR5 in monocytes exposed to HIV-1 mediates protection from activation-induced apoptosis: ex vivo and in vitro study

Por Gekonge, Bethsebah, Raymond, Andrea D., Yin, Xiangfan, Kostman, Jay, Mounzer, Karam, Collman, Ronald G., Showe, Louise, Montaner, Luis J.
Publicado em 2012

A Correlate of HIV-1 Control Consisting of Both Innate and Adaptive Immune Parameters Best Predicts Viral Load by Multivariable Analysis in HIV-1 Infected Viremic Controllers and C...

Por Tomescu, Costin, Liu, Qin, Ross, Brian N., Yin, Xiangfan, Lynn, Kenneth, Mounzer, Karam C., Kostman, Jay R., Montaner, Luis J.
Publicado em 2014

Plasmacytoid dendritic cell and functional HIV Gag p55-specific T cells before treatment interruption can inform set-point plasma HIV viral load after treatment interruption in chr...

Por Papasavvas, Emmanouil, Foulkes, Andrea, Yin, Xiangfan, Joseph, Jocelin, Ross, Brian, Azzoni, Livio, Kostman, Jay R, Mounzer, Karam, Shull, Jane, Montaner, Luis J
Publicado no Immunology (2015)

Metabolic and anthropometric parameters contribute to ART-mediated CD4(+ )T cell recovery in HIV-1-infected individuals: an observational study

Por Azzoni, Livio, Foulkes, Andrea S, Firnhaber, Cynthia, Yin, Xiangfan, Crowther, Nigel J, Glencross, Deborah, Lawrie, Denise, Stevens, Wendy, Papasavvas, Emmanouil, Sanne, Ian, Montaner, Luis J
Publicado em 2011

Effects of Immunosuppression on Circulating Adeno-Associated Virus Capsid-Specific T cells in Humans

Por Parzych, Elizabeth M., Li, Hua, Yin, Xiangfan, Liu, Qin, Wu, Te-Lang, Podsakoff, Gregory M., High, Katherine A., Levine, Matthew H., Ertl, Hildegund C.J.
Publicado em 2013

Increased Microbial Translocation in ≤180 Days Old Perinatally Human Immunodeficiency Virus Positive Infants as Compared with Human Immunodeficiency Virus -Exposed/Uninfected Infan...

Por PAPASAVVAS, EMMANOUIL, AZZONI, LIVIO, FOULKES, ANDREA, VIOLARI, AVY, COTTON, MARK F., PISTILLI, MAXWELL, REYNOLDS, GRIFFIN, YIN, XIANGFAN, GLENCROSS, DEBORAH K., STEVENS, WENDY S., MCINTYRE, JAMES A., MONTANER, LUIS J.
Publicado em 2011

Randomized Trial of Time-Limited Interruptions of Protease Inhibitor-Based Antiretroviral Therapy (ART) vs. Continuous Therapy for HIV-1 Infection

Por Firnhaber, Cynthia, Azzoni, Livio, Foulkes, Andrea S., Gross, Robert, Yin, Xiangfan, Van Amsterdam, Desiree, Schulze, Doreen, Glencross, Deborah K., Stevens, Wendy, Hunt, Gillian, Morris, Lynn, Fox, Lawrence, Sanne, Ian, Montaner, Luis J.
Publicado em 2011

High-risk oncogenic HPV genotype infection associates with increased immune activation and T cell exhaustion in ART-suppressed HIV-1-infected women

Por Papasavvas, Emmanouil, Surrey, Lea F., Glencross, Deborah K., Azzoni, Livio, Joseph, Jocelin, Omar, Tanvier, Feldman, Michael D., Williamson, Anna-Lise, Siminya, Maureen, Swarts, Avril, Yin, Xiangfan, Liu, Qin, Firnhaber, Cynthia, Montaner, Luis J.
Publicado no Oncoimmunology (2016)

Association between HIV replication and serum leptin levels: an observational study of a cohort of HIV-1-infected South African women

Por Azzoni, Livio, Crowther, Nigel J, Firnhaber, Cynthia, Foulkes, Andrea S, Yin, Xiangfan, Glencross, Deborah, Gross, Robert, Kaplan, Mitch D, Papasavvas, Emmanouil, Schulze, Doreen, Stevens, Wendy, van der Merwe, Tessa, Waisberg, Rita, Sanne, Ian, Montaner, Luis J
Publicado em 2010

Serial Cervicovaginal exposures with Replication-deficient SIVsm induce higher Dendritic Cell (pDC) and CD4+ T-Cell Infiltrates not associated with prevention but a More Severe SIV...

Por ABDULHAQQ, Shaheed A., MARTINEZ, Melween I., KANG, Guobin, FOULKES, Andrea S., RODRIGUEZ, Idia V., NICHOLS, Stephanie M., HUNTER, Meredith, SARIOL, Carlos A., RUIZ, Lynnette A., ROSS, Brian N., YIN, Xiangfan, SPEICHER, David W., HAASE, Ashley T., MARX, Preston A., LI, Qinsheng, KRAISELBURD, Edmundo N., MONTANER, Luis J.
Publicado em 2014

PIM kinases as therapeutic targets against advanced melanoma

Por Shannan, Batool, Watters, Andrea, Chen, Quan, Mollin, Stefan, Dörr, Markus, Meggers, Eric, Xu, Xiaowei, Gimotty, Phyllis A., Perego, Michela, Li, Ling, Benci, Joseph, Krepler, Clemens, Brafford, Patricia, Zhang, Jie, Wei, Zhi, Zhang, Gao, Liu, Qin, Yin, Xiangfan, Nathanson, Katherine L., Herlyn, Meenhard, Vultur, Adina
Publicado no Oncotarget (2016)

HIV-1 Negative Female Sex Workers Sustain High Cervical IFNε, Low Immune Activation and Low Expression of HIV-1 Required Host Genes

Por Abdulhaqq, Shaheed A., Zorrilla, Carmen, Kang, Guobin, Yin, Xiangfan, Tamayo, Vivian, Seaton, Kelly E., Joseph, Jocelin, Garced, Sheyla, Tomaras, Georgia D., Linn, Kristin A., Foulkes, Andrea S., Azzoni, Livio, VerMilyea, Matthew, Coutifaris, Christos, Kossenkov, Andrew V., Showe, Louise, Kraiselburd, Edmundo N., Li, Qingsheng, Montaner, Luis J.
Publicado no Mucosal Immunol (2015)

HSP70 inhibition limits FAK-dependent invasion and enhances the response to melanoma treatment with BRAF inhibitors

Por Budina-Kolomets, Anna, Webster, Marie R., Leu, Julia I-Ju, Jennis, Matthew, Krepler, Clemens, Guerrini, Anastasia, Kossenkov, Andrew V., Xu, Wei, Karakousis, Giorgos, Schuchter, Lynn, Amaravadi, Ravi K., Wu, Hong, Yin, Xiangfan, Liu, Qin, Lu, Yiling, Mills, Gordon B., Xu, Xiaowei, George, Donna L., Weeraratna, Ashani T., Murphy, Maureen E.
Publicado no Cancer Res (2016)

BET inhibitors suppress ALDH activity by targeting ALDH1A1 super-enhancer in ovarian cancer

Por Yokoyama, Yuhki, Zhu, Hengrui, Lee, Jeong Heon, Kossenkov, Andrew V., Wu, Sherry Y., Wickramasinghe, Jayamanna M., Yin, Xiangfan, Palozola, Katherine C., Gardini, Alessandro, Showe, Louise C., Zaret, Kenneth S., Liu, Qin, Speicher, David, Conejo-Garcia, Jose R., Bradner, James E., Zhang, Zhiguo, Sood, Anil K., Ordog, Tamas, Bitler, Benjamin G., Zhang, Rugang
Publicado no Cancer Res (2016)

Hypoxia induces phenotypic plasticity and therapy resistance in melanoma via the tyrosine kinase receptors ROR1 and ROR2

Por O’Connell, Michael P., Marchbank, Katie, Webster, Marie R., Valiga, Alexander A., Kaur, Amanpreet, Vultur, Adina, Li, Ling, Herlyn, Meenhard, Villanueva, Jessie, Liu, Qin, Yin, Xiangfan, Widura, Sandy, Nelson, Janelle, Ruiz, Nivia, Camilli, Tura C., Indig, Fred E., Flaherty, Keith T., Wargo, Jennifer A., Frederick, Dennie T., Cooper, Zachary A., Nair, Suresh, Amaravadi, Ravi K., Schuchter, Lynn M., Karakousis, Giorgos C., Xu, Wei, Xu, Xiaowei, Weeraratna, Ashani T.
Publicado em 2013

Co‐targeting BET and MEK as salvage therapy for MAPK and checkpoint inhibitor‐resistant melanoma

Por Echevarría‐Vargas, Ileabett M, Reyes‐Uribe, Patricia I, Guterres, Adam N, Yin, Xiangfan, Kossenkov, Andrew V, Liu, Qin, Zhang, Gao, Krepler, Clemens, Cheng, Chaoran, Wei, Zhi, Somasundaram, Rajasekharan, Karakousis, Giorgos, Xu, Wei, Morrissette, Jennifer JD, Lu, Yiling, Mills, Gordon B, Sullivan, Ryan J, Benchun, Miao, Frederick, Dennie T, Boland, Genevieve, Flaherty, Keith T, Weeraratna, Ashani T, Herlyn, Meenhard, Amaravadi, Ravi, Schuchter, Lynn M, Burd, Christin E, Aplin, Andrew E, Xu, Xiaowei, Villanueva, Jessie
Publicado no EMBO Mol Med (2018)

Genetic and genomic characterization of 462 melanoma patient-derived xenografts, tumor biopsies and cell lines

Por Garman, Bradley, Anastopoulos, Ioannis N., Krepler, Clemens, Brafford, Patricia, Sproesser, Katrin, Jiang, Yuchao, Wubbenhorst, Bradley, Amaravadi, Ravi, Bennett, Joseph, Beqiri, Marilda, Elder, David, Flaherty, Keith T., Frederick, Dennie T., Gangadhar, Tara C., Guarino, Michael, Hoon, David, Karakousis, Giorgos, Liu, Qin, Mitra, Nandita, Petrelli, Nicholas J., Schuchter, Lynn, Shannan, Batool, Shields, Carol L., Wargo, Jennifer, Wenz, Brandon, Wilson, Melissa A., Xiao, Min, Xu, Wei, Xu, Xaiowei, Yin, Xiangfan, Zhang, Nancy R., Davies, Michael A., Herlyn, Meenhard, Nathanson, Katherine L.
Publicado no Cell Rep (2017)

sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance

Por Kaur, Amanpreet, Webster, Marie R., Marchbank, Katie, Behera, Reeti, Ndoye, Abibatou, Kugel, Curtis H., Dang, Vanessa M., Appleton, Jessica, O’Connell, Michael P., Cheng, Phil, Valiga, Alexander A., Morissette, Rachel, McDonnell, Nazli B., Ferrucci, Luigi, Kossenkov, Andrew V., Meeth, Katrina, Tang, Hsin-Yao, Yin, Xiangfan, Wood, William H., Lehrmann, Elin, Becker, Kevin G., Flaherty, Keith T., Frederick, Dennie T., Wargo, Jennifer A., Cooper, Zachary A., Tetzlaff, Michael T., Hudgens, Courtney, Aird, Katherine M., Zhang, Rugang, Xu, Xiaowei, Liu, Qin, Bartlett, Edmund, Karakousis, Giorgos, Eroglu, Zeynep, Lo, Roger S., Chan, Matthew, Menzies, Alexander M., Long, Georgina V., Johnson, Douglas B., Sosman, Jeffrey, Schilling, Bastian, Schadendorf, Dirk, Speicher, David W., Bosenberg, Marcus, Ribas, Antoni, Weeraratna, Ashani T.
Publicado no Nature (2016)

A comprehensive patient-derived xenograft collection representing the heterogeneity of melanoma

Por Krepler, Clemens, Sproesser, Katrin, Brafford, Patricia, Beqiri, Marilda, Garman, Bradley, Xiao, Min, Shannan, Batool, Watters, Andrea, Perego, Michela, Zhang, Gao, Vultur, Adina, Yin, Xiangfan, Liu, Qin, Anastopoulos, Ioannis N, Wubbenhorst, Bradley, Wilson, Melissa A., Xu, Wei, Karakousis, Giorgos, Feldman, Michael, Xu, Xiaowei, Amaravadi, Ravi, Gangadhar, Tara C., Elder, David E., Haydu, Lauren E., Wargo, Jennifer A., Davies, Michael A., Lu, Yiling, Mills, Gordon B., Frederick, Dennie T., Barzily-Rokni, Michal, Flaherty, Keith T., Hoon, Dave S., Guarino, Michael, Bennett, Joseph J., Ryan, Randall W., Petrelli, Nicholas J, Shields, Carol L., Terai, Mizue, Sato, Takami, Aplin, Andrew E., Roesch, Alexander, Darr, David, Angus, Steve, Kumar, Rakesh, Halilovic, Ensar, Caponigro, Giordano, Jeay, Sebastien, Wuerthner, Jens, Walter, Annette, Ocker, Matthias, Boxer, Matthew B., Schuchter, Lynn, Nathanson, Katherine L., Herlyn, Meenhard
Publicado no Cell Rep (2017)