Hypoxia induces phenotypic plasticity and therapy resistance in melanoma via the tyrosine kinase receptors ROR1 and ROR2

An emerging concept in melanoma biology is that of dynamic, adaptive phenotype switching, where cells switch from a highly proliferative, poorly invasive phenotype to a highly invasive, less proliferative one. This switch may hold significant implications not just for metastasis, but also for therap...

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Main Authors: O’Connell, Michael P., Marchbank, Katie, Webster, Marie R., Valiga, Alexander A., Kaur, Amanpreet, Vultur, Adina, Li, Ling, Herlyn, Meenhard, Villanueva, Jessie, Liu, Qin, Yin, Xiangfan, Widura, Sandy, Nelson, Janelle, Ruiz, Nivia, Camilli, Tura C., Indig, Fred E., Flaherty, Keith T., Wargo, Jennifer A., Frederick, Dennie T., Cooper, Zachary A., Nair, Suresh, Amaravadi, Ravi K., Schuchter, Lynn M., Karakousis, Giorgos C., Xu, Wei, Xu, Xiaowei, Weeraratna, Ashani T.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918498/
https://ncbi.nlm.nih.gov/pubmed/24104062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-13-0005
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