The Orphan Tyrosine Kinase Receptor, ROR2, Mediates Wnt5A Signaling in Metastatic Melanoma

Tyrosine kinase receptors represent targets of great interest for cancer therapy. Here we demonstrate, for the first time, the importance of the orphan tyrosine kinase receptor, ROR2, in melanoma progression. Using melanoma tissue microarrays we show that ROR2 is expressed predominantly in metastati...

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Bibliografiske detaljer
Main Authors: O’Connell, Michael P., Fiori, Jennifer L., Xu, Mai, Carter, Arnell D., Frank, Brittany P., Camilli, Tura C., French, Amanda D., Dissanayake, Samudra K., Indig, Fred E., Bernier, Michel, Taub, Dennis D., Hewitt, Stephen M., Weeraratna, Ashani T.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2803338/
https://ncbi.nlm.nih.gov/pubmed/19802008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.305
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