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Effects of Immunosuppression on Circulating Adeno-Associated Virus Capsid-Specific T cells in Humans

In humans adeno-associated virus (AAV)-mediated gene transfer is followed by expansion of AAV capsid-specific T cells, evidence of cell damage, and loss of transgene product expression, implicating immunological rejection of vector-transduced cells, which may be prevented by immunosuppressive drugs....

詳細記述

保存先:
書誌詳細
主要な著者: Parzych, Elizabeth M., Li, Hua, Yin, Xiangfan, Liu, Qin, Wu, Te-Lang, Podsakoff, Gregory M., High, Katherine A., Levine, Matthew H., Ertl, Hildegund C.J.
フォーマット: Artigo
言語:Inglês
出版事項: Mary Ann Liebert, Inc. 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631016/
https://ncbi.nlm.nih.gov/pubmed/23461589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2012.246
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