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Effects of Immunosuppression on Circulating Adeno-Associated Virus Capsid-Specific T cells in Humans
In humans adeno-associated virus (AAV)-mediated gene transfer is followed by expansion of AAV capsid-specific T cells, evidence of cell damage, and loss of transgene product expression, implicating immunological rejection of vector-transduced cells, which may be prevented by immunosuppressive drugs....
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3631016/ https://ncbi.nlm.nih.gov/pubmed/23461589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2012.246 |
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