AAV capsid CD8+ T-cell epitopes are highly conserved across AAV serotypes

Adeno-associated virus (AAV) has become one of the most promising vectors in gene transfer in the last 10 years with successful translation to clinical trials in humans and even market approval for a first gene therapy product in Europe. Administration to humans, however, revealed that adaptive immu...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Mol Ther Methods Clin Dev
Main Authors: Hui, Daniel J, Edmonson, Shyrie C, Podsakoff, Gregory M, Pien, Gary C, Ivanciu, Lacramioara, Camire, Rodney M, Ertl, Hildegund, Mingozzi, Federico, High, Katherine A, Basner-Tschakarjan, Etiena
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588448/
https://ncbi.nlm.nih.gov/pubmed/26445723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2015.29
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker