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AAV capsid CD8+ T-cell epitopes are highly conserved across AAV serotypes
Adeno-associated virus (AAV) has become one of the most promising vectors in gene transfer in the last 10 years with successful translation to clinical trials in humans and even market approval for a first gene therapy product in Europe. Administration to humans, however, revealed that adaptive immu...
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| Udgivet i: | Mol Ther Methods Clin Dev |
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| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4588448/ https://ncbi.nlm.nih.gov/pubmed/26445723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2015.29 |
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