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Cell-Mediated Immunity to AAV Vectors, Evolving Concepts and Potential Solutions

Adeno-associated virus (AAV) vectors are one of the most efficient in vivo gene delivery platforms. Over the past decade, clinical trials of AAV vector-mediated gene transfer led to some of the most exciting results in the field of gene therapy and, recently, to the market approval of an AAV-based d...

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Bibliografiske detaljer
Main Authors: Basner-Tschakarjan, Etiena, Mingozzi, Federico
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4107954/
https://ncbi.nlm.nih.gov/pubmed/25101090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00350
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