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T Cell-Mediated Immune Responses to AAV and AAV Vectors

Adeno-associated virus (AAV)-mediated gene transfer has benefited patients with inherited diseases, such as hemophilia B, by achieving long-term expression of the therapeutic transgene. Nevertheless, challenges remain due to rejection of AAV-transduced cells, which in some, but not all, patients can...

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Pubblicato in:Front Immunol
Autore principale: Ertl, Hildegund C. J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8076552/
https://ncbi.nlm.nih.gov/pubmed/33927727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.666666
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