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Challenges Posed by Immune Responses to AAV Vectors: Addressing Root Causes
Host immune responses that limit durable therapeutic gene expression and cause clinically significant inflammation remain a major barrier to broadly successful development of adeno-associated virus (AAV)-based human gene therapies. In this article, mechanisms of humoral and cellular immune responses...
Shranjeno v:
| izdano v: | Front Immunol |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Frontiers Media S.A.
2021
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8168460/ https://ncbi.nlm.nih.gov/pubmed/34084173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.675897 |
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