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Depletion of FAP(+) cells reduces immunosuppressive cells and improves metabolism and functions CD8(+)T cells within tumors
The tumor stroma, which is essential to support growth and metastasis of malignant cells, provides targets for active immunotherapy of cancer. Previous studies have shown that depleting fibroblast activation protein (FAP)-expressing stromal cells reduces tumor progression and concomitantly increases...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5029626/ https://ncbi.nlm.nih.gov/pubmed/26943036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7818 |
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