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Depletion of FAP(+) cells reduces immunosuppressive cells and improves metabolism and functions CD8(+)T cells within tumors

The tumor stroma, which is essential to support growth and metastasis of malignant cells, provides targets for active immunotherapy of cancer. Previous studies have shown that depleting fibroblast activation protein (FAP)-expressing stromal cells reduces tumor progression and concomitantly increases...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Zhang, Ying, Ertl, Hildegund C.J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029626/
https://ncbi.nlm.nih.gov/pubmed/26943036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7818
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