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Starved and Asphyxiated: How Can CD8(+) T Cells within a Tumor Microenvironment Prevent Tumor Progression

Although cancer immunotherapy has achieved significant breakthroughs in recent years, its overall efficacy remains limited in the majority of patients. One major barrier is exhaustion of tumor antigen-specific CD8(+) tumor-infiltrating lymphocytes (TILs), which conventionally has been attributed to...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Zhang, Ying, Ertl, Hildegund C. J.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748049/
https://ncbi.nlm.nih.gov/pubmed/26904023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00032
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