HDAC9 deficiency promotes tumor progression by decreasing the CD8(+) dendritic cell infiltration of the tumor microenvironment

BACKGROUND: The tumor microenvironment (TME) contains a variety of immune cells, which play critical roles during the multistep development of tumors. Histone deacetylase 9 (HDAC9) has been reported to have either proinflammatory or anti-inflammatory effects, depending on the immune environment. In...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Ning, Yongling, Ding, Jun, Sun, Xiao, Xie, Yewen, Su, Mingming, Ma, Chenglong, Pan, Jie, Chen, Jie, Jiang, Hua, Qi, Chunjian
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2020
Assuntos:
Basic Tumor Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7304847/
https://ncbi.nlm.nih.gov/pubmed/32554611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-000529
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