Lysis of HIV-1 Infected Autologous CD4(+) Primary T cells by Interferon-alpha Activated NK cells Requires NKp46 and NKG2D

Por Tomescu, Costin, Mavilio, Domenico, Montaner, Luis J.
Publicado no AIDS (2015)

IFN-α augments natural killer-mediated antibody-dependent cellular cytotoxicity of HIV-1-infected autologous CD4(+) T cells regardless of major histocompatibility complex class 1 d...

Por Tomescu, Costin, Tebas, Pablo, Montaner, Luis J.
Publicado no AIDS (2017)

Surface Downregulation of Major Histocompatibility Complex Class I, PE-CAM, and ICAM-1 following De Novo Infection of Endothelial Cells with Kaposi's Sarcoma-Associated Herpesvirus

Por Tomescu, Costin, Law, Wai K., Kedes, Dean H.
Publicado em 2003

Retention of viability, cytotoxicity, and response to IL-2, IL-15, or IFN-α by human NK cells after CD107a degranulation

Por Tomescu, Costin, Chehimi, Jihed, Maino, Vernon C., Montaner, Luis J.
Publicado em 2009

Intracellular Kaposi's Sarcoma-Associated Herpesvirus Load Determines Early Loss of Immune Synapse Components

Por Adang, Laura A., Tomescu, Costin, Law, Wai K., Kedes, Dean H.
Publicado em 2007

S100A14 IS INCREASED IN ACTIVATED NK CELLS AND PLASMA OF HIV-EXPOSED SERONEGATIVE PEOPLE WHO INJECT DRUGS AND PROMOTES MONOCYTE-NK CROSSTALK.

Por Colón, Krystal, Speicher, David W., Smith, Peter, Taylor, Mack, Metzger, David S., Montaner, Luis J., Tomescu, Costin
Publicado no J Acquir Immune Defic Syndr (2019)

Innate Activation of MDC and NK Cells in High-risk HIV-1 Exposed, Sero-Negative (HESN) IV-Drug Users that Share Needles When Compared to Low-risk Non-sharing IV-Drug User Controls

Por Tomescu, Costin, Seaton, Kelly E., Smith, Peter, Taylor, Mack, Tomaras, Georgia D., Metzger, David S., Montaner, Luis J.
Publicado no J Acquir Immune Defic Syndr (2015)

A Correlate of HIV-1 Control Consisting of Both Innate and Adaptive Immune Parameters Best Predicts Viral Load by Multivariable Analysis in HIV-1 Infected Viremic Controllers and C...

Por Tomescu, Costin, Liu, Qin, Ross, Brian N., Yin, Xiangfan, Lynn, Kenneth, Mounzer, Karam C., Kostman, Jay R., Montaner, Luis J.
Publicado em 2014

Impact of Protective KIR/HLA Genotypes on NK Cell and T Cell Function in HIV-1 Infected Controllers

Por Tomescu, Costin, Duh, Fuh-Mei, Hoh, Rebecca, Viviani, Anne, Harvill, Kara, Martin, Maureen P., Carrington, Mary, Deeks, Steven G., Montaner, Luis J.
Publicado em 2012

Increased Plasmacytoid Dendritic Cell Maturation and Natural Killer Cell Activation in HIV-1 Exposed, Uninfected Intra-venous Drug Users

Por Tomescu, Costin, Duh, Fuh-Mei, Lanier, Michael A., Kapalko, Angela, Mounzer, Karam C., Martin, Maureen P., Carrington, Mary, Metzger, David S., Montaner, Luis J.
Publicado em 2010

BCL6 Inhibitor-Mediated Downregulation of Phosphorylated SAMHD1 and T Cell Activation Are Associated with Decreased HIV Infection and Reactivation

Por Cai, Yanhui, Abdel-Mohsen, Mohamed, Tomescu, Costin, Xue, Fengtian, Wu, Guoxin, Howell, Bonnie J., Ai, Yong, Sun, Jie, Azzoni, Livio, Le Coz, Carole, Romberg, Neil, Montaner, Luis J.
Publicado no J Virol (2019)

Inability of Plasmacytoid Dendritic Cells To Directly Lyse HIV-Infected Autologous CD4(+) T Cells despite Induction of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand

Por Chehimi, Jihed, Papasavvas, Emmanouil, Tomescu, Costin, Gekonge, Bethsebah, Abdulhaqq, Shaheed, Raymond, Andrea, Hancock, Aidan, Vinekar, Kavita, Carty, Craig, Reynolds, Griffin, Pistilli, Maxwell, Mounzer, Karam, Kostman, Jay, Montaner, Luis J.
Publicado em 2010

The role of CD32 during HIV-1 infection

Por Bertagnolli, Lynn N., White, Jennifer A., Simonetti, Francesco R., Beg, Subul A., Lai, Jun, Tomescu, Costin, Murray, Alexandra J., Antar, Annukka A. R., Zhang, Hao, Margolick, Joseph B., Hoh, Rebecca, Deeks, Steven G., Tebas, Pablo, Montaner, Luis J., Siliciano, Robert F., Laird, Gregory M., Siliciano, Janet D.
Publicado no Nature (2018)

Anti-α4β7 therapy targets lymphoid aggregates in the gastrointestinal tract of HIV-1–infected individuals

Por Uzzan, Mathieu, Tokuyama, Minami, Rosenstein, Adam K., Tomescu, Costin, SahBandar, Ivo N., Ko, Huaibin M., Leyre, Louise, Chokola, Anupa, Kaplan-Lewis, Emma, Rodriguez, Gabriela, Seki, Akihiro, Corley, Michael J., Aberg, Judith, La Porte, Annalena, Park, Eun-young, Ueno, Hideki, Oikonomou, Ioannis, Doron, Itai, Iliev, Iliyan D., Chen, Benjamin K., Lui, Jennifer, Schacker, Timothy W., Furtado, Glaucia C., Lira, Sergio A., Colombel, Jean-Frederic, Horowitz, Amir, Lim, Jean K., Chomont, Nicolas, Rahman, Adeeb H., Montaner, Luis J., Ndhlovu, Lishomwa C., Mehandru, Saurabh
Publicado no Sci Transl Med (2018)

CD32 is expressed on cells with transcriptionally active HIV but does not enrich for HIV DNA in resting T cells

Por Abdel-Mohsen, Mohamed, Kuri-Cervantes, Leticia, Grau-Exposito, Judith, Spivak, Adam M., Nell, Racheal A., Tomescu, Costin, Vadrevu, Surya Kumari, Giron, Leila B., Serra-Peinado, Carla, Genescà, Meritxell, Castellví, Josep, Wu, Guoxin, Del Rio Estrada, Perla M., González-Navarro, Mauricio, Lynn, Kenneth, King, Colin T., Vemula, Sai, Cox, Kara, Wan, Yanmin, Li, Qingsheng, Mounzer, Karam, Kostman, Jay, Frank, Ian, Paiardini, Mirko, Hazuda, Daria, Reyes-Terán, Gustavo, Richman, Douglas, Howell, Bonnie, Tebas, Pablo, Martinez-Picado, Javier, Planelles, Vicente, Buzon, Maria J., Betts, Michael R., Montaner, Luis J.
Publicado no Sci Transl Med (2018)