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Surface Downregulation of Major Histocompatibility Complex Class I, PE-CAM, and ICAM-1 following De Novo Infection of Endothelial Cells with Kaposi's Sarcoma-Associated Herpesvirus

Under selective pressure from host cytotoxic T lymphocytes, many viruses have evolved to downregulate major histocompatibility complex (MHC) class I and/or T-cell costimulatory molecules from the surface of infected cells. Kaposi's sarcoma-associated herpesvirus (KSHV) encodes two proteins, MIR...

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Detalhes bibliográficos
Main Authors: Tomescu, Costin, Law, Wai K., Kedes, Dean H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC187401/
https://ncbi.nlm.nih.gov/pubmed/12915579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.17.9669-9684.2003
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