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Retention of viability, cytotoxicity, and response to IL-2, IL-15, or IFN-α by human NK cells after CD107a degranulation

NK cells represent a critical component of the host innate immune response to viral infection and tumor transformation. Nevertheless, the fate of recently degranulated NK cells subsequent to a primary target cell interaction remains largely unexplored. Here, we investigated the long-term viability a...

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Autori principali: Tomescu, Costin, Chehimi, Jihed, Maino, Vernon C., Montaner, Luis J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Society for Leukocyte Biology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669410/
https://ncbi.nlm.nih.gov/pubmed/19237639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1008635
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