IFN-γ-deficient mice develop IL-1-dependent cutaneous and musculoskeletal inflammation during experimental brucellosis

Human brucellosis exhibits diverse pathological manifestations that can affect almost any organ. In particular, osteoarticular complications are the most common focal manifestation of brucellosis and occur in 40–80% of patients. In immunocompetent mice, Brucella replication is generally restricted t...

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Detalhes bibliográficos
Main Authors: Skyberg, Jerod A., Thornburg, Theresa, Kochetkova, Irina, Layton, William, Callis, Gayle, Rollins, MaryClare F., Riccardi, Carol, Becker, Todd, Golden, Sarah, Pascual, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2012
Assuntos:
Host Defense & Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395417/
https://ncbi.nlm.nih.gov/pubmed/22636321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1211626
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