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Hematopoietic MyD88 and IL-18 are essential for IFN-γ–dependent restriction of type A Francisella tularensis infection

Francisella tularensis is a highly infectious intracellular bacterium that causes the potentially fatal disease tularemia. We used mice with conditional MyD88 deficiencies to investigate cellular and molecular mechanisms by which MyD88 restricts type A F. tularensis infection. F. tularensis–induced...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Skyberg, Jerod A., Lacey, Carolyn A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669634/
https://ncbi.nlm.nih.gov/pubmed/28951422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.4A0517-179R
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