IFN-γ-deficient mice develop IL-1-dependent cutaneous and musculoskeletal inflammation during experimental brucellosis

Human brucellosis exhibits diverse pathological manifestations that can affect almost any organ. In particular, osteoarticular complications are the most common focal manifestation of brucellosis and occur in 40–80% of patients. In immunocompetent mice, Brucella replication is generally restricted t...

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Main Authors: Skyberg, Jerod A., Thornburg, Theresa, Kochetkova, Irina, Layton, William, Callis, Gayle, Rollins, MaryClare F., Riccardi, Carol, Becker, Todd, Golden, Sarah, Pascual, David W.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Leukocyte Biology 2012
Assuntos:
Host Defense & Pathophysiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395417/
https://ncbi.nlm.nih.gov/pubmed/22636321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1211626
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