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Diminished secretion and function of IL‐29 is associated with impaired IFN‐α response of neonatal plasmacytoid dendritic cells

Plasmacytoid dendritic cells (pDCs) are key players in the antiviral immune response and type III IFNs such as IL‐29 appear to play a pivotal role in pDC function. Pronounced susceptibility to viral infections in neonates is partly resulting from diminished antiviral immune mechanisms. Accordingly,...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Wisgrill, Lukas, Wessely, Isabelle, Netzl, Antonia, Pummer, Linda, Sadeghi, Kambis, Spittler, Andreas, Berger, Angelika, Förster‐Waldl, Elisabeth
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6852569/
https://ncbi.nlm.nih.gov/pubmed/31211458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.4A0518-189R
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