GM-CSF Down-Regulates TLR Expression via the Transcription Factor PU.1 in Human Monocytes

Toll-like receptors (TLR) are crucial sensors of microbial agents such as bacterial or viral compounds. These receptors constitute key players in the induction of inflammation, e.g. in septic or chronic inflammatory diseases. Colony-stimulating factors (CSFs) such as granulocyte-macrophage-CSF (GM-C...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sadeghi, Kambis, Wisgrill, Lukas, Wessely, Isabelle, Diesner, Susanne C., Schüller, Simone, Dürr, Celia, Heinle, Armando, Sachet, Monika, Pollak, Arnold, Förster-Waldl, Elisabeth, Spittler, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5047522/
https://ncbi.nlm.nih.gov/pubmed/27695085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162667
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