CD32 is expressed on cells with transcriptionally active HIV but does not enrich for HIV DNA in resting T cells

The persistence of HIV reservoirs, including latently infected, resting CD4(+) T cells, is the major obstacle to cure HIV infection. CD32a expression was recently reported to m ark CD4(+) T cells harboring a replication-competent HIV reservoir during antiretroviral therapy (ART) suppression. We aime...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Abdel-Mohsen, Mohamed, Kuri-Cervantes, Leticia, Grau-Exposito, Judith, Spivak, Adam M., Nell, Racheal A., Tomescu, Costin, Vadrevu, Surya Kumari, Giron, Leila B., Serra-Peinado, Carla, Genescà, Meritxell, Castellví, Josep, Wu, Guoxin, Del Rio Estrada, Perla M., González-Navarro, Mauricio, Lynn, Kenneth, King, Colin T., Vemula, Sai, Cox, Kara, Wan, Yanmin, Li, Qingsheng, Mounzer, Karam, Kostman, Jay, Frank, Ian, Paiardini, Mirko, Hazuda, Daria, Reyes-Terán, Gustavo, Richman, Douglas, Howell, Bonnie, Tebas, Pablo, Martinez-Picado, Javier, Planelles, Vicente, Buzon, Maria J., Betts, Michael R., Montaner, Luis J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282755/
https://ncbi.nlm.nih.gov/pubmed/29669853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aar6759
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