Common tolerance mechanisms, but distinct cross-reactivities associated with gp41 and lipids, limit production of HIV-1 broad neutralizing antibodies 2F5 and 4E10()

door Chen, Yao, Zhang, Jinsong, Hwang, Kwan-Ki, Bouton-Verville, Hilary, Xia, Shi-Mao, Newman, Amanda, Ouyang, Ying-Bin, Haynes, Barton F., Verkoczy, Laurent
Gepubliceerd in 2013

A polymorphism in the HCP5 gene associated with HLA-B*5701 does not restrict HIV-1 in vitro

door Yoon, Woohyun, Ma, Ben-Jiang, Fellay, Jacques, Huang, Wei, Xia, Shi-Mao, Zhang, Ruijun, Shianna, Kevin V., Liao, Hua-Xin, Haynes, Barton F., Goldstein, David B.
Gepubliceerd in 2010

Role of HIV membrane in neutralization by two broadly neutralizing antibodies

door Alam, S. Munir, Morelli, Marco, Dennison, S. Moses, Liao, Hua-Xin, Zhang, Ruijun, Xia, Shi-Mao, Rits-Volloch, Sophia, Sun, Li, Harrison, Stephen C., Haynes, Barton F., Chen, Bing
Gepubliceerd in 2009

Nonneutralizing HIV-1 gp41 Envelope Cluster II Human Monoclonal Antibodies Show Polyreactivity for Binding to Phospholipids and Protein Autoantigens

door Dennison, S. Moses, Anasti, Kara, Scearce, Richard M., Sutherland, Laura, Parks, Robert, Xia, Shi-Mao, Liao, Hua-Xin, Gorny, Miroslaw K., Zolla-Pazner, Susan, Haynes, Barton F., Alam, S. Munir
Gepubliceerd in 2011

High throughput functional analysis of HIV-1 env genes without cloning

door Kirchherr, Jennifer L, Lu, Xiaozhi, Kasongo, Webster, Chalwe, Victor, Mwananyanda, Lawrence, Musonda, Rosemary M, Xia, Shi-Mao, Scearce, Richard M, Liao, Hua-Xin, Montefiori, David C, Haynes, Barton F, Gao, Feng
Gepubliceerd in 2007

Selection of immunoglobulin elbow region mutations impacts interdomain conformational flexibility in HIV-1 broadly neutralizing antibodies

door Henderson, Rory, Watts, Brian E., Ergin, Hieu N., Anasti, Kara, Parks, Robert, Xia, Shi-Mao, Trama, Ashley, Liao, Hua-Xin, Saunders, Kevin O., Bonsignori, Mattia, Wiehe, Kevin, Haynes, Barton F., Alam, S. Munir
Gepubliceerd in Nat Commun (2019)

Induction of HIV-1 broad neutralizing antibodies in 2F5 knockin mice: selection against MPER-associated autoreactivity limits T-dependent responses

door Verkoczy, Laurent, Chen, Yao, Zhang, Jinsong, Bouton-Verville, Hilary, Newman, Amanda, Lockwood, Bradley, Scearce, Richard M., Montefiori, David C., Dennison, S. Moses, Xia, Shi-Mao, Hwang, Kwan-Ki, Liao, Hua-Xin, Alam, S.Munir, Haynes, Barton F.
Gepubliceerd in 2013

Development of a Recombinant Yellow Fever Vector Expressing a HIV Clade C Founder Envelope gp120

door Yu, Jae-Sung, Liao, Hua-Xin, Pritchett, Jamie, Bowman, Cindy, Vivian, Callie, Parks, Robert, Xia, Shi-Mao, Cooper, Melissa, Williams, Wilton B, Bonsignori, Mattia, Reed, Steven G., Chen, Meng, Vandergrift, Nathan, Rice, Charles M., Haynes, Barton F.
Gepubliceerd in J Virol Methods (2017)

Isolation of HIV-1-Neutralizing Mucosal Monoclonal Antibodies from Human Colostrum

door Friedman, James, Alam, S. Munir, Shen, Xiaoying, Xia, Shi-Mao, Stewart, Shelley, Anasti, Kara, Pollara, Justin, Fouda, Genevieve G., Yang, Guang, Kelsoe, Garnett, Ferrari, Guido, Tomaras, Georgia D., Haynes, Barton F., Liao, Hua-Xin, Moody, M. Anthony, Permar, Sallie R.
Gepubliceerd in 2012

RAB11FIP5-Deficient Mice Exhibit Cytokine-Related Transcriptomic Signatures

door Li, Dapeng, Bradley, Todd, Cain, Derek W., Pedroza-Pacheco, Isabela, Aggelakopoulou, Maria, Parks, Robert, Barr, Maggie, Xia, Shi-Mao, Scearce, Richard, Bowman, Cindy, Stevens, Grace, Newman, Amanda, Hora, Bhavna, Chen, Yue, Riebe, Kristina, Wang, Yunfei, Sempowski, Gregory, Saunders, Kevin O., Borrow, Persephone, Haynes, Barton F.
Gepubliceerd in Immunohorizons (2020)

A Group M Consensus Envelope Glycoprotein Induces Antibodies That Neutralize Subsets of Subtype B and C HIV-1 Primary Viruses

door Liao, Hua-Xin, Sutherland, Laura L., Xia, Shi-Mao, Brock, Mary E., Scearce, Richard M., Vanleeuwen, Stacie, Alam, S. Munir, McAdams, Mildred, Weaver, Eric A., Camacho, Zenaido T., Ma, Ben-Jiang, Li, Yingying, Decker, Julie M., Nabel, Gary J., Montefiori, David C., Hahn, Beatrice H., Korber, Bette T., Gao, Feng, Haynes, Barton F.
Gepubliceerd in 2006

Induction of Antibodies in Rhesus Macaques That Recognize a Fusion-Intermediate Conformation of HIV-1 gp41

door Dennison, S. Moses, Sutherland, Laura L., Jaeger, Frederick H., Anasti, Kara M., Parks, Robert, Stewart, Shelley, Bowman, Cindy, Xia, Shi-Mao, Zhang, Ruijun, Shen, Xiaoying, Scearce, Richard M., Ofek, Gilad, Yang, Yongping, Kwong, Peter D., Santra, Sampa, Liao, Hua-Xin, Tomaras, Georgia, Letvin, Norman L., Chen, Bing, Alam, S. Munir, Haynes, Barton F.
Gepubliceerd in 2011

Human Immunodeficiency Virus Type 1 gp41 Antibodies That Mask Membrane Proximal Region Epitopes: Antibody Binding Kinetics, Induction, and Potential for Regulation in Acute Infecti...

door Alam, S. Munir, Scearce, Richard M., Parks, Robert J., Plonk, Kelly, Plonk, Steven G., Sutherland, Laura L., Gorny, Miroslaw K., Zolla-Pazner, Susan, VanLeeuwen, Stacie, Moody, M. Anthony, Xia, Shi-Mao, Montefiori, David C., Tomaras, Georgia D., Weinhold, Kent J., Karim, Salim Abdool, Hicks, Charles B., Liao, Hua-Xin, Robinson, James, Shaw, George M., Haynes, Barton F.
Gepubliceerd in 2008

Antigenicity and Immunogenicity of Transmitted/Founder, Consensus, and Chronic Envelope Glycoproteins of Human Immunodeficiency Virus Type 1

door Liao, Hua-Xin, Tsao, Chun-Yen, Alam, S. Munir, Muldoon, Mark, Vandergrift, Nathan, Ma, Ben-Jiang, Lu, Xiaozhi, Sutherland, Laura L., Scearce, Richard M., Bowman, Cindy, Parks, Robert, Chen, Haiyan, Blinn, Julie H., Lapedes, Alan, Watson, Sydeaka, Xia, Shi-Mao, Foulger, Andrew, Hahn, Beatrice H., Shaw, George M., Swanstrom, Ron, Montefiori, David C., Gao, Feng, Haynes, Barton F., Korber, Bette
Gepubliceerd in 2013

IGHV1-69 B Cell Chronic Lymphocytic Leukemia Antibodies Cross-React with HIV-1 and Hepatitis C Virus Antigens as Well as Intestinal Commensal Bacteria

door Hwang, Kwan-Ki, Trama, Ashley M., Kozink, Daniel M., Chen, Xi, Wiehe, Kevin, Cooper, Abby J., Xia, Shi-Mao, Wang, Minyue, Marshall, Dawn J., Whitesides, John, Alam, Munir, Tomaras, Georgia D., Allen, Steven L., Rai, Kanti R., McKeating, Jane, Catera, Rosa, Yan, Xiao-Jie, Chu, Charles C., Kelsoe, Garnett, Liao, Hua-Xin, Chiorazzi, Nicholas, Haynes, Barton F.
Gepubliceerd in 2014

Toll-Like Receptor 7/8 (TLR7/8) and TLR9 Agonists Cooperate To Enhance HIV-1 Envelope Antibody Responses in Rhesus Macaques

door Moody, M. Anthony, Santra, Sampa, Vandergrift, Nathan A., Sutherland, Laura L., Gurley, Thaddeus C., Drinker, Mark S., Allen, Ashley A., Xia, Shi-Mao, Meyerhoff, R. Ryan, Parks, Robert, Lloyd, Krissey E., Easterhoff, David, Alam, S. Munir, Liao, Hua-Xin, Ward, Brandy M., Ferrari, Guido, Montefiori, David C., Tomaras, Georgia D., Seder, Robert A., Letvin, Norman L., Haynes, Barton F.
Gepubliceerd in 2014

Immunodominance of antibody recognition of the HIV envelope second variable region in immunoglobulin humanized mice

door Wiehe, Kevin, Nicely, Nathan I., Lockwood, Bradley, Kuraoka, Masayuki, Anasti, Kara, Arora, Sabrina, Bowman, Cindy M., Stolarchuk, Christina, Parks, Robert, Lloyd, Krissey E., Xia, Shi-Mao, Duffy, Ryan, Shen, Xiaoying, Kyratsous, Christos A., Macdonald, Lynn E., Murphy, Andrew J., Scearce, Richard M., Moody, M. Anthony, Alam, S. Munir, Verkoczy, Laurent, Tomaras, Georgia D., Kelsoe, Garnett, Haynes, Barton F.
Gepubliceerd in J Immunol (2016)

Cooperation of B Cell Lineages in Induction of HIV-1-Broadly Neutralizing Antibodies

door Gao, Feng, Bonsignori, Mattia, Liao, Hua-Xin, Kumar, Amit, Xia, Shi-Mao, Lu, Xiaozhi, Cai, Fangping, Hwang, Kwan-Ki, Song, Hongshuo, Zhou, Tongqing, Lynch, Rebecca M., Alam, S. Munir, Moody, M. Anthony, Ferrari, Guido, Berrong, Mark, Kelsoe, Garnett, Shaw, George M., Hahn, Beatrice H., Montefiori, David C., Kamanga, Gift, Cohen, Myron, Hraber, Peter, Kwong, Peter D., Korber, Bette T., Mascola, John R., Kepler, Thomas B., Haynes, Barton F.
Gepubliceerd in 2014

Inference of the HIV-1 VRC01 Antibody Lineage Unmutated Common Ancestor Reveals Alternative Pathways to Overcome a Key Glycan Barrier

door Bonsignori, Mattia, Scott, Eric, Wiehe, Kevin, Easterhoff, David, Alam, S. Munir, Hwang, Kwan-Ki, Cooper, Melissa, Xia, Shi-Mao, Zhang, Ruijun, Montefiori, David C., Henderson, Rory, Nie, Xiaoyan, Kelsoe, Garnett, Moody, M. Anthony, Chen, Xuejun, Joyce, M. Gordon, Kwong, Peter D., Connors, Mark, Mascola, John R., McGuire, Andrew T., Stamatatos, Leonidas, Medina-Ramírez, Max, Sanders, Rogier W., Saunders, Kevin O., Kepler, Thomas B., Haynes, Barton F.
Gepubliceerd in Immunity (2018)

Amino Acid Changes in the HIV-1 gp41 Membrane Proximal Region Control Virus Neutralization Sensitivity

door Bradley, Todd, Trama, Ashley, Tumba, Nancy, Gray, Elin, Lu, Xiaozhi, Madani, Navid, Jahanbakhsh, Fatemeh, Eaton, Amanda, Xia, Shi-Mao, Parks, Robert, Lloyd, Krissey E., Sutherland, Laura L., Scearce, Richard M., Bowman, Cindy M., Barnett, Susan, Abdool-Karim, Salim S., Boyd, Scott D., Melillo, Bruno, Smith, Amos B., Sodroski, Joseph, Kepler, Thomas B., Alam, S.Munir, Gao, Feng, Bonsignori, Mattia, Liao, Hua-Xin, Moody, M. Anthony, Montefiori, David, Santra, Sampa, Morris, Lynn, Haynes, Barton F.
Gepubliceerd in EBioMedicine (2016)